I don't think an in-game injury is very concerning. The odds are low and if it happens you just yank the DH and pinch hit for the pitchers the rest of the game. Even IF that happens, it's not guaranteed to cost the game. You could be up by 6 runs when it happens or down by 6 and the injury doesn't affect the outcome. Or the injury could happen in the 8th and you wouldn't even need to pinch hit.