Missing the playoffs would be brutal, especially with the extra WC, but I wouldn't be overreacting and firing anyone just yet.
There was some pretty big career years last season, but now this season some of the players might be having abnormally unproductive seasons, and nobody on the roster is having a surprisingly "good" season save for maybe Gausman, but even he has been unlucky as hell when it comes to final results. Vlad at 2.9 fWAR? Bo at 2.3 fWAR? Berrios at 0.5 fWAR?
The team is set up for a 2 year run as it is right now (with some off season tweaking). I'd let that play out and hope that the players can make the necessary adjustments, along with a couple of tweaks on the roster that will hopefully vault them to legit contender level.
If they haven't found success after the 2023 season, then I'd be looking to make some major changes from top to bottom.