If they are out of it at the deadline? I don't see why not. There's no qualifying offer getting them an extra 1st anymore. Estrada, Liriano, and Bautista (assuming he waives his NTC) are all free agents at the end of the season (dem options on Jose won't be picked up). A quick retool for 2018 isn't out of the question.
Anyway, too early to have this discussion. 1-5 (if they can't eek out a comeback today) is nothing this early in the season.