If I was Commish, I would do 4 divisions of 8 teams. (2 AL, 2 NL). Back to pre-90s expansion divisions. Play each team within division 8 times (2 x 4 games) each team in other division 6 times (2 x 3 games) each team in other league 3 or 4 times alternating home games between divisions each year like now (play 4 games vs NLE, 3 games vs NLW). This would create a more balanced schedule and make more 4 game series and less travel overall. 160 game season. Each League has 6 playoff teams (2 Division winners, 4 WC teams).4 Division winners get bye in WC round. WC and DS rounds are best of 5, AL/NL and WS best of 7. This puts more importance back on winning your division.
AL East - Tor, Bos, NYY, Bal, TB, Det, Cle, CWS
AL West - Sea, Port (new), LAA, Tex, Hou, KC, Ath, Min
NL East - Phi, NYM, Was, Atl, Pit,Cin,Nash (new), Mia
NL West - LAD, SD, Ari, SF, Col, Mil, Stl, CHC