Yeah Kloff would be an aggressive callup but should be considered.
I think they should demote Manoah after the game no matter who they call up. For starters, his performance warrants it and whatever AAA slop that replaces him won't be any worse. They can call up Kloff or just use some slop like Zach Thompson until Francis is ready.
Second, this play is just completely unacceptable and some changes need to be made. Sloppy base running, lethargic defense, garbage ABs, etc. The division has basically slipped away and it's going to be a dogfight to make the WC now in what looks like a pretty competitive year for it with the AL West being more competitive.
So we need to make some changes. Manoah should be demoted, the hitting coach should get canned (it's not his fault but heads should roll), and they should also consider doing something like demoting Biggio and calling up Horwitz (no idea where he plays).