That second list you named, the plenty of guys who became legit major leaguers. It's a really mediocre list to be honest. Three good/great first rounders and a handful of decent major leaguers, you'll probably get that in most classes, but look at any other year prior, and the list of notable guys is just generally a lot longer. Since we're talking about 2005 already, here's a partial list of some names that were in that class for comparison:
1st rounders: Upton, Gordon, Zimmerman, Braun, Romero, Tulowitzki, McCutchen, Bruce, Ellsbury, Garza, Lowrie, Buchholz
Notables: Headley, Yunel, Gardner, Brantley, Pearce, Jackson, Bourjos, Joyce, Garcia, Romo, Hanson
Others: Reimold, Wood, Slowey, Hundley, Hellickson, Estrada, Niese, Venable, Richard, Lannan, Badenhop, Morrison
Selected but not signed: Posey, Lincecum, Axford, Davis, Avila, Cashner, Worley, Miley, Davis, Jennings, Smoak, Alonso, Hunter, Bailey, Alvarez, Fister, Lynn, Matusz