Yeah I can't imagine Romano would have been sharp after throwing 2 innings and 29 pitches as well. I think you would have needed a combination of Stripling and Berrios to take you maybe into the 7th, and throw in guys like Pop, Bass, Phelps and Richards for sure. Garcia, Cimber and Mayza likely still would have been available, though who knows how sharp they would be after being used 3 consecutive days. Or use Stripling for the first and maybe second time through the order, use some relievers in the middle and then have Berrios close it out.
Mariners would have been short handed as well, so definitely would have been an interesting game.