No he's never going to be an average runner and he has little legs because how short he is. But the load it would take off his body and the fludity he would get in his body would definitely improve his performance running where he could be less of base clogger. Without question being lighter improves your bodies mechanics. Its why you see a lot of NBA players especially big man trim down later in their career. LeBron is playing at his lightest weight since he was a teenager. Dwight Howard is another example. Look how lean he was with the Lakers compared to where he was in his prime.