I like the bigger bases, even if they just increase the efficiency of steals by a bit. There isn't any downside to that change.
I don't think the shift ban is going to have that big of an effect. Teams are still going to place their infielders right on the boundaries. I hope it doesn't lead to a bunch of nitpicky challenges, which would be bad for the game.
The pitch clock is going to be a nightmare to enforce and lead to a bunch of controversial calls, as we saw at times in the minor leagues. I'm not convinced that this is a positive change, but I'm willing to give it a chance.
The worst part of this announcement in my opinion is what it does not include. Mainly, changes to the Posey rule and an automated strike zone.
I'm hopeful that it's exclusion from the list means that extra innings will go back to normal. It's almost universally seen as a negative amongst fans and media, according to polls.