If he gives up more than 2 base runners you obviously get Osuna up at that point. I don't care about the save statistic at all. You can argue Boogers saved us in the first with that bunt.
I would like to see one of your other back end options with a 4 run lead because you could have a one run lead against the Tigers tomorrow and now we have to use Grilli, Biagini, or Storen anyway. Osuns threw close to 30 pitches today. And a lot on Friday if I remember correctly.