If it's in that 25-30 range, definitely not.
Depending on the draft (some are much deeper than others), but usually, once you get passed that top 15-20....players between 21-50 are very interchangeable. It isn't unlike baseball...you have your top tier guys that you know are going early...but at a certain point you can get guys ranked 80th taken at the end of the 1st round.